Autophagy lecture PDF Print E-mail
Wednesday, 11 January 2017 02:33

Within the cultural season for Tropical Biological Research Unit / College of Science/ Baghdad University for the academic year 2016/2017, Dr. Maisa'a Kadom Hebesh delivered the scientific titled lecture:

"Autophagy How and Why"

In the main debate Hall of the Unit


meaning "self-devouring" is the natural, regulated, destructive mechanism of the cell that disassembles unnecessary or dysfunctional components. Autophagy allows the orderly degradation and recycling of cellular components. In macro autophagy, targeted cytoplasmic constituents are isolated from the rest of the cell within a double-membrane vesicle known as an autophagosome the autophagosome eventually fuses with lysosomes and the contents are degraded and recycled.

   Three additional forms of autophagy are also commonly described:

-       Micro autophagy

-       Macriautophagy

-       Chaperone-Mediated Autophagy (CMA).

In disease diagnosing, autophagy has been seen as an adaptive response to stress, which promotes survival, whereas in other cases it appears to promote cell death and morbidity. In the extreme case of starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels




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